A felnőttkori hypolactasia születésikohorsz-vizsgálata

DNA test for hypolactasia premature

I write in response to the article by Rasinperä and colleagues (Gut 2004;53:1571–6) in which a DNA test was proposed for ‘‘adulttype hypolactasia’’. The ability to digest the milk sugar lactose as an adult (lactase persistence) is a variable genetic trait in human populations, lactase persistence being the most frequent phenotype in Northern Europe, while lactase nonpersistence or ‘‘adult-type ...

ADULT-TYPE HYPOLACTASIA: Genotype-phenotype correlation

Hypolactasia as a molecular basis of lactose intolerance.

Lactase-phlorizin hydrolase (LPH), a membrane-bound glycoprotein present in the luminal surface of enterocytes in the intestine is responsible for lactose intolerance, a phenomenon prevalent in humans worldwide. In the rodent intestine, the post-natal development of the LPH follows a specific pattern, such that the enzyme levels are high in the peri-natal period, but declines considerably upon ...

Genetic Aspects of Adult-Type Hypolactasia

Background and objective: Lactose is a disaccharide sugar and is found in mammals milk and derivatives. Lactose intolerance is the inability to metabolize lactose, because of a lack of the required enzyme lactase in the digestive system. Genetically the physiological hypolactasia (primary LM) is associated with the LCT-13910 C/T and LCT-22018 G/A polymorphisms. The aim of this study focused on ...

Genetic Testing of Adult-type Hypolactasia